Publications
Our teams aspire to make discoveries that impact everyone, and core to our approach is sharing our research and tools to fuel progress in the field.
Our teams aspire to make discoveries that impact everyone, and core to our approach is sharing our research and tools to fuel progress in the field.
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1 - 15 of 11369 publications
A Dynamic Numerical Model for Real-Time Estimation of Latent Cognitive States Using Oculomotor Metrics
Diako Mardanbegi
ICASSP 2026-2026 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), pp. 22087-22091
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Estimating internal cognitive states from oculomotor data is fundamentally challenging due to their context-dependency and the complex relationship between various metrics. This paper proposes a dynamic numerical framework to model a task-specific behavioral signature and monitor deviations from it in real-time. The model integrates key oculomotor and motion metrics into a differential equation, yielding a continuous score that serves as an estimate of a latent cognitive state. By using tunable, heuristic parameters, our approach offers a transparent and adaptable alternative to opaque machine learning models. The framework’s strength lies in its ability to pinpoint objective changes in behavior, providing a potential tool for interpreting events like the onset of fatigue, distraction, or cognitive load.
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We prove the following asymptotically tight lower bound for k-color discrepancy: For any k ≥ 2, there exists a hypergraph with n vertices such that its k-color discrepancy is at least Ω(√n). This improves on the previously known lower bound of Ω(√n/ log k) due to Caragiannis et al. [CLS25]. As an application, we show that our result implies improved lower bounds for group fair division.
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Expert evaluation of LLM world models: A high-Tc superconductivity case study
Haoyu Guo
Maria Tikhanovskaya
Paul Raccuglia
Alexey Vlaskin
Chris Co
Scott Ellsworth
Matthew Abraham
Lizzie Dorfman
Peter Armitage
Chunhan Feng
Antoine Georges
Olivier Gingras
Dominik Kiese
Steve Kivelson
Vadim Oganesyan
Brad Ramshaw
Subir Sachdev
Senthil Todadri
John Tranquada
Eun-Ah Kim
Proceedings of the National Academy of Sciences (2026)
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Large Language Models (LLMs) show great promise as a powerful tool for scientific literature exploration. However, their effectiveness in providing scientifically accurate and comprehensive answers to complex questions within specialized domains remains an active area of research. This work evaluates the performance of six different LLM-based systems for answering scientific literature questions, including commercially available closed models and a custom retrieval-augmented generation (RAG) system capable of retrieving images alongside text. We conduct a rigorous expert evaluation of the systems in the domain of high-temperature cuprate superconductors, a research area that involves material science, experimental physics, computation, and theoretical physics. We use an expert-curated database of 1726 scientific papers and a set of 67 expert-formulated questions. The evaluation employs a multi-faceted rubric assessing balanced perspectives, factual comprehensiveness, succinctness, evidentiary support, and image relevance. Our results demonstrate that RAG-based systems, powered by curated data and multimodal retrieval, outperform existing closed models across key metrics, particularly in providing comprehensive and well-supported answers, and in retrieving relevant visual information. This study provides valuable insights into designing and evaluating specialized scientific literature understanding systems, particularly with expert involvement, while also highlighting the importance of rich, domain-specific data in such systems.
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On-the-Fly OVD Adaptation with FLAME: Few-shot Localization via Active Marginal-Samples Exploration
Yehonathan Refael
Amit Aides
Aviad Barzilai
Vered Silverman
Bolous Jaber
Proceedings of the IEEE/CVF Winter Conference on Applications of Computer Vision (WACV) Workshops (2026), pp. 886-894
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Open-vocabulary object detection (OVD) models offer remarkable flexibility applications by enabling object detection from arbitrary text queries. Still, the zero-shot performance of the pre-trained models is hampered by the inherent semantic ambiguity of natural language, result to low precision, leading to insufficient crucial downstream applications. For instance, in the remote sensing (RS) domain, a query for "ship" can yield varied and contextually irrelevant results. To address this, for real time applications, we propose a novel cascaded architecture that synergizes the broad capabilities of a large, pre-trained OVD model with a lightweight, few-shot classifier. Our approach utilizes the frozen weights of the zero-shot model to generate initial, high-recall object-embedding proposals, which are then refined by a compact classifier trained in real-time on a handful of user-annotated examples. The core of our contribution is an efficient one step active learning strategy for selecting the most informative samples for user annotation. Our method identifies (extremely) small amount of an uncertain candidates near the theoretical decision boundary using density estimation and then applies clustering to ensure a diverse training set. This targeted sampling enables our cascaded system to elevate performance on standard remote sensing benchmarks. Our work thus presents a practical and resource-efficient framework for adapting foundational models to specific user needs, drastically reducing annotation overhead while achieving high accuracy without costly full-model fine-tuning.
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This defensive publication describes a framework for multi-artificial intelligence (AI) orchestration that can be used to address potential limitations associated with reliance on single AI models, such as correlated systemic failures or cognitive blind spots. The described system is a cognitive orchestration framework that can function as a middleware layer to manage tasks across a heterogeneous ensemble of AI models. An orchestrator node can decompose a user request into a sequence of sub-tasks, which an arbitrage engine may then dynamically assign to suitable AI models based on certain factors, such as capability, cost, and latency. For certain tasks, such as those designated as high-risk, a byzantine consensus layer can route the task to multiple diverse models in parallel and may trigger a process, for example a 'cognitive debate,' which could be adjudicated by a third-party judge model to help resolve conflicting outputs. This framework can facilitate a more resilient system that may improve the accuracy and reliability of outputs when compared to some single-model architectures.
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We study the fair allocation of indivisible goods with variable groups. In this model, the goal is to partition the agents into groups of given sizes and allocate the goods to the groups in a fair manner. We show that for any number of groups and corresponding sizes, there always exists an envy-free up to one good (EF1) outcome, thereby generalizing an important result from the individual setting. Our result holds for arbitrary monotonic utilities and comes with an efficient algorithm. We also prove that the EF1 existence can be guaranteed even when the goods lie on a path and each group must receive a connected bundle. In addition, we consider a probabilistic model where the utilities are additive and drawn randomly from a distribution. We show that if there are n agents and the number of goods m is divisible by the number of groups k, then an envy-free outcome exists with high probability if m = ω(log n), and this bound is tight. On the other hand, if m is not divisible by k, then an envy-free outcome is unlikely to exist as long as m = o(√n).
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Neural general circulation models for modeling precipitation
Stephan Hoyer
Dmitrii Kochkov
Janni Yuval
Ian Langmore
Science Advances (2026)
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Climate models struggle to accurately simulate precipitation, particularly extremes and the diurnal cycle. While hybrid models combining machine learning and physics have emerged with the premise of improving precipitation simulations, none have proven sufficiently skillful or stable enough to outperform existing models in simulating precipitation.
Here, we present the first hybrid model that is trained directly on precipitation observations. The model runs at 2.8 degrees resolution and is built on the differentiable NeuralGCM framework. This model is stable for decadal simulations and demonstrates significant improvements over existing GCMs, ERA5 reanalysis, and a Global Cloud-Resolving Model in simulating precipitation. Our approach yields reduced biases, a more realistic precipitation distribution, improved representation of extremes, and a more accurate diurnal cycle.
Furthermore, it outperforms the ECMWF ensemble for mid-range weather forecasting.
This advance paves the way for more reliable simulations of current climate and for the ability to fully utilize the abundance of existing observations to further improve GCMs.
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This writeup defines the Hydration Proxy Pattern, a framework for building stateful conversational data systems over stateless LLM APIs. It describes a platform-agnostic approach to decoupling persistence from the AI provider through secure server-side intermediation and hybrid storage tiers. The abstract provides a blueprint for managing the "Persistence Gap" in enterprise AI integrations, detailing high-level strategies for session history management, streaming, and multi-stage semantic grounding without disclosing specific internal implementation details.
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Sexual dimorphism in the complete connectome of the Drosophila male central nervous system
Stuart Berg
Isabella R Beckett
Marta Costa
Philipp Schlegel
Elizabeth C Marin
Aljoscha Nern
Stephan Preibisch
Wei Qiu
Shin-ya Takemura
Andrew Champion
Reed A. George
Gary Huang
William Katz
Christopher Ordish
Ken Hayworth
Eric Trautman
Vivek Jayaraman
Wyatt Korff
Geoffrey W Meissner
Sandro Romani
Jan Funke
Christopher Knecht
Stephan Saalfeld
Louis Scheffer
Scott Waddell
Gwyneth Card
Carlos Ribeiro
Michael B. Reiser
Harald Hess
Gerry Rubin
Gregory S.X.E. Jefferis
bioRxiv (2026)
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Sex differences in behaviour exist across all animals, typically under strong genetic regulation. In Drosophila, fruitless/doublesex transcription factors can identify dimorphic neurons but their organisation into functional circuits remains unclear.
We present the connectome of the entire Drosophila male central nervous system. This contains 166,691 neurons spanning the brain and nerve cord, fully proofread and annotated including fruitless/doublesex expression and 11,691 types. We provide the first comprehensive comparison between male and female brain connectomes to synaptic resolution, finding 7,205 isomorphic, 114 dimorphic, 262 male-specific and 69 female-specific types.
This resource enables analysis of full sensory-to-motor circuits underlying complex behaviours and the impact of dimorphic elements. Sex-specific/dimorphic neurons are concentrated in higher brain centres while the sensory and motor periphery are largely isomorphic. Within higher centres, male-specific connections are organised into hotspots defined by male-specific neurons or arbours. Numerous circuit switches reroute sensory information to form antagonistic circuits controlling opposing behaviours.
(Full author list included with the paper.)
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Gaze Target Estimation Anywhere with Concepts
Xu Cao
Houze Yang
Vipin Gunda
Inki Kim
Jim Rehg
Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition (2026)
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Estimating human gaze targets in-the-wild is a formidable challenge. Existing computer vision algorithms rely on brittle, multi-stage pipelines that require explicit inputs like head bounding boxes and human pose, causing initial detection errors to cascade and lead to system failure. To overcome this, we introduce the \textbf{Promptable Gaze Target Estimation (PGE)} task, a new end-to-end, concept-driven paradigm. PGE conditions gaze prediction on flexible user text or visual prompts (e.g., "the boy in the red shirt" or "person in point [0.52, 0.48]") to identify a specific subject's target, which eliminates the rigid dependency on intermediate localization cues. We develop a scalable data engine to generate \textbf{Gaze-Co}, a dataset and benchmark of 120K high-quality, prompt-annotated image pairs. We also propose \textbf{AnyGaze}, the first model designed for PGE. AnyGaze uses a Transformer-based detector to fuse features from frozen encoders and simultaneously solves subject localization, in/out-of-frame presence, and gaze target heatmap estimation. AnyGaze achieves state-of-the-art performance on standard gaze target estimation benchmarks, setting a strong baseline for this new problem even on a difficult out-of-domain, real-world clinical dataset. We will open-source the AnyGaze model and the Gaze-Co benchmark.
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PURPOSE: To introduce Cardio Load (CL), a metric quantifying cardiovascular work from all activities across the day, and to investigate its distribution by age, gender, and workout profiles. CL adapts the Training Impulse (TRIMP) model by leveraging continuous heart rate and movement data from wearables, enabling minute-level intensity estimation. We also discuss the derivation of weekly target loads, intended to guide fitness maintenance.
METHODS: A retrospective analysis was conducted on 31.2 million hours of wrist-worn wearable data collected over a six-week period. The dataset comprised a 40,000-subject subset (37.9% female) of consenting Google Pixel Watch® users in the United States, aged 18 to 80 years (18-39: 41.8%, 40-59: 43.5%, 60+: 14.6%). Measured data included minute-interval heart rate averages, resting and maximum heart rates, minute-interval averaged accelerometer log energy, and manually-logged or auto-detected activity types. Cardio Load scores and target loads were calculated daily for each subject and compared across age and gender. We also compared the proportions of CL gained during workouts and incidental daily activities for these groups.
RESULTS: Overall, the study population's mean ± SD weekly CL scores were 221 ± 156 (female) and 259 ± 169 (male). Median weekly Cardio Load (CL) values exhibited consistency for individuals between 30 and 75 years of age. When analyzed in five-year age groups, the coefficient of variation (CV%) of median weekly CL values within this age range was less than 4.5%, with younger and older subjects demonstrating higher and lower median CL, respectively. The median proportion of CL accumulated during structured workouts versus incidental daily activity was 41.0% (female) and 49.0% (male) for all subjects, though this varied considerably with average weekly workout duration. CV% of weekly target load and daily target load over 6 weeks was 23.6% and 35.2% respectively.
CONCLUSION: Cardio Load provides a continuous quantification of activity load from wearables, acknowledging both structured workouts and everydayincidental activity. CL is equitably rewarded for age ranges spanning 30-75 years. Weekly target loads were found to have little measurement variability and be more consistent and, consequently, more practical for planning training and physical activity than daily targets.
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Object-Counting for remote-sensing (RS) imagery is raising increasing research interest due to its crucial role in a wide and diverse set of applications. While several promising methods for RS object-counting have been proposed, existing methods focus on a closed, pre-defined set of object classes. This limitation necessitates costly re-annotation and model re-training to adapt current approaches for counting of novel objects that have not been seen during training, and severely inhibits their application in dynamic, real-world monitoring scenarios.
To address this gap, in this work we propose RS-OVC - an adaptation of existing work for Open Vocabulary Counting (OVC) approach from general computer vision to the RS domain. We show that our model is capable of accurate counting of novel object classes, that are unseen during training, based solely on textual and/or visual conditioning.
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High-volume enterprise service organizations face a persistent challenge in transitioning from reactive support models to proactive, preventative ones. This paper introduces the Agentic Trend-to-Knowledge (ATK) methodology, a novel, autonomous framework designed to address this gap. The ATK methodology employs an AI agent that operates in a recurring, closed loop. It first uses a two-stage process for the autonomous thematic analysis of recent support cases to identify the most significant recurring issue. It then leverages Retrieval-Augmented Generation (RAG) to source relevant institutional knowledge. A key innovation is the agent's adaptive, bimodal response: if relevant knowledge is found, it drafts a proactive communication for human review; if a knowledge gap is detected, it autonomously creates a content creation task for the appropriate team. This transforms the agent from an automation tool into a proactive process owner that creates a virtuous cycle of continuous improvement for both case deflection and knowledge base quality. By automating the entire workflow from insight to action, the ATK framework provides a concrete methodology for shifting from a "human-in-the-loop" to a more strategic "human-on-the-loop" operational paradigm.
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In some multi-stage software build pipelines, downstream compiler errors may be reported against ephemeral, machine-generated intermediate artifacts rather than original, human-written source code, which can make remediation challenging. A system and method may address this by intercepting a downstream error, mapping its location back to the original source file, and programmatically injecting a dormant suppression tag into the original source code. During a subsequent build, an intermediate transpiler can propagate this tag into a newly generated intermediate artifact. In the intermediate file, the tag may become active and be recognized by the downstream compiler as a directive to suppress the specific error. This approach can facilitate an automated remediation process for certain build failures that avoids direct modification of ephemeral files and uses the original source code as a record for suppression.
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We study the d-dimensional knapsack problem. We are given a set of items, each with a d-dimensional cost vector and a profit, along with a d-dimensional budget vector. The goal is to select a set of items that do not exceed the budget in all dimensions and maximize the total profit. A polynomial-time approximation scheme (PTAS) with running time n^{Θ(d/{ε})} has long been known for this problem, where {ε} is the error parameter and n is the encoding size. Despite decades of active research, the best running time of a PTAS has remained O(n^{⌈ d/{ε} ⌉ - d}). Unfortunately, existing lower bounds only cover the special case with two dimensions d = 2, and do not answer whether there is a n^{o(d/({ε)})}-time PTAS for larger values of d.
In this work, we show that the running times of the best-known PTAS cannot be improved up to a polylogarithmic factor assuming the Exponential Time Hypothesis (ETH). Our techniques are based on a robust reduction from 2-CSP, which embeds 2-CSP constraints into a desired number of dimensions. Then, using a recent result of [Bafna Karthik and Minzer, STOC'25], we succeed in exhibiting tight trade-off between d and {ε} for all regimes of the parameters assuming d is sufficiently large. Informally, our result also shows that under ETH, for any function f there is no f(d/({ε)}) ⋅ n^{õ(d/({ε)})}-time (1-{ε})-approximation for d-dimensional knapsack, where n is the number of items and õ hides polylogarithmic factors in d/({ε)}.
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