General Science

The DNS root zone was first signed with DNSSEC in 2010. On October 11, 2018 the DNSSEC Key Signing Key (KSK) was first rolled in the root zone. Having now completed that first roll, the Internet Assigned Numbers Authority (IANA) has asked the ICANN Community to respond to its plan for subsequent KSK rollovers. The SSAC would like to thank ICANN, and specifically IANA, for engaging with the...

Symbolic regression is a type of discrete optimization problem that involves searching expressions that fit given data points. In many cases, other mathematical constraints about the unknown expression not only provide more information beyond just values at some inputs, but also effectively constrain the search space. We identify the asymptotic constraints of leading polynomial powers as the...

Background: Automated machine-learning systems are able to de-identify electronic medical records, including free-text clinical notes. Use of such systems would greatly boost the amount of data available to researchers, yet their deployment has been limited due to uncertainty about their performance when applied to new datasets. Objective: We present practical options for clinical note de-...

Lyme disease is the most common tick-borne disease in the Northern Hemisphere. Existing estimates of Lyme disease spread are delayed a year or more. We introduce Lymelight—a new method for monitoring the incidence of Lyme disease in real-time. We use a machine-learned classifier of web search sessions to estimate the number of individuals who search for possible Lyme disease symptoms in a given...