Publications
Our teams aspire to make discoveries that impact everyone, and core to our approach is sharing our research and tools to fuel progress in the field.
Our teams aspire to make discoveries that impact everyone, and core to our approach is sharing our research and tools to fuel progress in the field.
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1 - 15 of 11361 publications
An AI system to help scientists write expert-level empirical software
Eser Aygün
Anastasiya Belyaeva
Gheorghe Comanici
Hao Cui
Renee Johnston
Zahra Shamsi
David Smalling
James Thompson
Sarah Martinson
Lai Wei
Yuchen Zhou
Qian-Ze Zhu
Matthew Abraham
Erica Brand
Anna Bulanova
Jeffrey Cardille
Chris Co
Scott Ellsworth
Grace Joseph
Malcolm Kane
Ryan Krueger
Johan Kartiwa
Jackson Cui
Paul Raccuglia
Julie Wang
Kat Chou
James Manyika
Lizzie Dorfman
Shibl Mourad
Nature (2026)
Preview abstract
The cycle of scientific discovery is frequently bottlenecked by the slow, manual creation of software to support computational experiments. To address this, we present Empirical Research Assistance (ERA), an AI system that creates expert-level scientific software whose goal is to maximize a quality metric. The system uses a Large Language Model (LLM) and Tree Search (TS) to systematically improve the quality metric and intelligently navigate the large space of possible solutions. ERA achieves expert-level results when it explores and integrates complex research ideas from external sources. The effectiveness of tree search is demonstrated across a diverse range of tasks. In bioinformatics, ERA discovered 40 novel methods for single-cell data analysis that outperformed the top human-developed methods on a public leaderboard. In epidemiology, ERA generated 14 models that outperformed the CDC ensemble and all other individual models for forecasting COVID-19 hospitalizations. ERA also produced expert-level software for geospatial analysis, neural activity prediction in zebrafish, and numerical solution of integrals, and a novel rule-based construction for time series forecasting. By devising and implementing novel solutions to diverse tasks, ERA represents a significant step towards accelerating scientific progress.
Keywords: Tree Search, Generative AI, Scorable Scientific Tasks, Empirical Software
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Generative AI (GenAI) is evolving from standalone tools to interconnected ecosystems that integrate chatbots, cloud platforms, and third-party services. While this ecosystem model enables personalization and extended services, it also introduces complex information flows and amplifies privacy risks. Existing solutions focus on system-level protections, offering little support for users to make meaningful privacy choices. To address this gap, we conducted two vignette-based survey studies with 486 participants and a followup interview study with 16 participants. We also explored users’ needs and preferences for privacy choice design across both GenAI personalization and data-sharing. Our results reveal paradoxical patterns: participants sometimes trusted third-party ecosystems more for personalization but perceived greater control in first-party ecosystems when data was shared externally. We discuss design implications for privacy choice interfaces that enhance transparency, control, and trust in GenAI ecosystems.
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Peeking Ahead of the Field Study: Exploring VLM Personas as Support Tools for Embodied Studies in HCI
Xinyue Gui
Ding Xia
Mark Colley
Yuan Li
Vishal Chauhan
Anubhav Anubhav
Ehsan Javanmardi
Stela Hanbyeol Seo
Chia-Ming Chang
Manabu Tsukada
Takeo Igarashi
Proceedings of the 2026 CHI Conference on Human Factors in Computing Systems (CHI 26)
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Field studies are irreplaceable but costly, time-consuming, and error-prone, which need careful preparation. Inspired by rapid-prototyping in manufacturing, we propose a fast, low-cost evaluation method using Vision-Language Model (VLM) personas to simulate outcomes comparable to field results. While LLMs show human-like reasoning and language capabilities, autonomous vehicle (AV)-pedestrian interaction requires spatial awareness, emotional empathy, and behavioral generation. This raises our research question: To what extent can VLM personas mimic human responses in field studies? We conducted parallel studies: 1) one real-world study with 20 participants, and 2) one video-study using 20 VLM personas, both on a street-crossing task. We compared their responses and interviewed five HCI researchers on potential applications. Results show that VLM personas mimic human response patterns (e.g., average crossing times of 5.25 s vs. 5.07 s) lack the behavioral variability and depth. They show promise for formative studies, field study preparation, and human data augmentation.
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"It didn’t feel right but I needed a job so desperately": Understanding People's Emotions & Help Needs During Financial Scams
G. Jake Chanenson
Tara Matthews
Jessica McClearn
Sarah Meiklejohn
Mia Hassoun
2026
Preview abstract
Online financial scams represent a long-standing and serious threat for which people seek help. We present a study to understand people’s in situ motivations for engaging with scams and the help needs they express before, during, and after encountering a scam. We identify the main emotions scammers exploited (e.g., fear, hope) and characterize how they did so. We examine factors—such as financial insecurity and legal precarity—which elevate people’s risk of engaging with specific scams and experiencing harm. We indicate when people sought help and describe their help-seeking needs and emotions at different stages of the scam. We discuss how these needs could be met through the design of contextually-specific prevention, diagnostic, mitigation, and recovery interventions.
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Ten Insights from Other Domains That Inform Responsible AI Frameworks
Allison Woodruff
Angela McKay
Dunstan Allison-Hope
Proceedings of the AAAI/ACM Conference on AI, Ethics, and Society (2026), 104–115
Preview abstract
The rapid growth of AI systems is being accompanied by new guidelines, principles, standards, regulations, and best practices (hereafter “frameworks”) that seek to ensure the responsible design, development, deployment, and use of AI systems.
Our premise is that the substance, implementation, and evolution of these AI frameworks can be informed by the practical experience of pursuing similar desired outcomes in other relevant domains (e.g., content moderation, human rights, climate change). This will help ensure that mistakes are not repeated and more rapid progress is made.
We used a “repetition test” to generate the following ten insights from other domains. Insights passing the “repetition test” are those that experts with thousands of hours of practical experience often repeat when describing the best practices that have emerged from their domain.
AI frameworks can draw from these ten insights, rather than invent entirely new approaches.
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**Agentic Engineering** is the rigorous discipline of treating Large Language Models as semi-autonomous systems that execute complex, multi-step workflows (trajectories) based on verifiable specifications, rather than using them as simple autocomplete engines.
Here is a brief summary of its core principles:
* **Main Goals:** It aims to maximize the agent's autonomous run-time, multiply a single engineer's impact by running parallel tasks, and offload tedious boilerplate coding.
* **The "Harness":** A raw model is virtually useless without heavy investment in a harness—comprising tools, system prompts, and strict guardrails—to reliably guide the model and enforce coding policies.
* **Loss of Micro-Control:** Engineers must surrender idiosyncratic stylistic preferences; if the agent's code passes automated linters and tests, it is accepted.
* **Meta-Debugging:** When failures occur, engineers no longer fix code syntax. Instead, they debug the workflow itself—adjusting the agent's tools, search queries, or prompt constraints to ensure repeatable success.
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DeduBB: Binary Code Size Reduction via Post-Link Basic Block De-duplication
Chaitanya Mamatha Ananda
Rajiv Gupta
Mahbod Afarin
Han Shen
LCTES (Languages, Compilers, Tools and Theory of Embedded Systems) (2026) (to appear)
Preview abstract
Binary sizes of newer versions of software applications tend to be larger, primarily due to feature bloat. This poses various challenges, particularly for mobile applications. It affects
upgrade rates directly impacting revenues, increases maintenance costs of supporting multiple versions, and prevents some users from getting critical security fixes. Code bloat also poses a problem for large warehouse-scale applications. Such applications experience performance degradation when their code size exceeds what smaller and more efficient code
models can handle.
In this paper, we introduce a post-link optimization tech nique called DeduBB, which deduplicates basic blocks of an application across procedure boundaries. While prior tech-
niques used function outlining to de-duplicate redundant code sequences, it missed out on many opportunities as it cannot handle code that manipulates the program stack. In addition, previous techniques were either limited to the scope of a module or lacked scalable implementations required to handle large warehouse-scale applications. Our technique,
DeduBB, handles all types of code duplication as we use a novel save-and-jump code pattern to execute de-duplicated code blocks. In addition, DeduBB has been designed to work on scalable post-link optimizers and can even be applied to large warehouse-scale datacenter applications. Finally, DeduBB is profile-guided and can be applied selectively to infrequently executed cold basic blocks to not affect application performance. In fact, in several cases, the performance
of the smaller application binary improves due to reductions in its hot working set size. We have implemented our technique on the state-of-the-art post link optimizers, BOLT and Propeller. Experiments show that we can significantly reduce the code size of several benchmarks by 1.55% to 18.63%, on both Arm and x86 platforms, and on binaries that have already been heavily optimized for size using existing code size reduction features. Furthermore, aided by profiles, our technique can retain more than 80% of the maximal code size savings without affecting performance.
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Causal Armor: Efficient Indirect Prompt Injection Guardrails via Causal Attribution
Minbeom Kim
Phil Wallis
Kyomin Jung
Dj Dvijotham
2026
Preview abstract
AI agents equipped with tool-calling capabilities are susceptible to \emph{Indirect Prompt Injection} (IPI) attacks. In this attack scenario, malicious commands hidden within \emph{untrusted} content trick the agent into performing unauthorized actions. Existing defenses can reduce attack success but often suffer from the \emph{over-defense dilemma}: they deploy expensive, \emph{always-on} sanitization that degrades utility and latency even in benign scenarios. We revisit IPI through an operational causal lens: a successful injection manifests as a \emph{grounding collapse} where the user request no longer provides decisive support for the agent's privileged action, while a particular untrusted segment provides disproportionate marginal support. Based on this signature, we propose \texttt{CausalArmor}, a selective defense framework that (i) computes lightweight, normalized leave-one-out attributions at privileged decision points, and (ii) triggers targeted sanitization only when an untrusted segment dominates the user intent. Additionally, CausalArmor employs \emph{retroactive Chain-of-Thought masking} to prevent the agent from acting on ``poisoned" reasoning traces. Experiments on AgentDojo and DoomArena demonstrate that CausalArmor matches the security of aggressive defenses with explainability while preserving utility and latency of AI agents.
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Observing long-lived longwave contrail forcing
Aarón Sonabend
Joe Ng
Atmospheric Measurement Techniques (2026)
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Contrail microphysical simulations and climate simulations have indicated that contrail cirrus cause a substantial fraction of aviation’s climate impact. While the approximations and parameter selections in these simulations have been well-validated over the past two decades, the heat trapping of contrails has not been observed using satellite data beyond a few hours. This is because contrails lose their linear shape after a few hours, making them difficult to distinguish from natural cirrus clouds. Here we provide satellite-driven analysis of long-lived heat trapping by contrails over North and South America. We aggregate a dataset of GOES-16 estimated outgoing longwave radiation and advected trace density of flight paths, and apply causal inference to discern the effect of contrails while controlling for radiative and cloud confounders. As a means of validation, we also generate synthetic datasets with known ground truth, and confirm that applying the causal inference method is able to recover the synthetic ground truth. Since this method yields an estimate which has some differences from both “instantaneous radiative forcing” (iRF) and “effective radiative forcing” (ERF) estimates which have been reported in the literature so far, we introduce the new term “observational radiative forcing, 12 hours” (oRF12). Our analysis estimates the longwave oRF12 from contrails over the Americas averaged 47.9 gigajoules per flight kilometer (95% CI: 31 to 52 GJ/km) during April 2019 to April 2020.
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How many T gates are needed to approximate an arbitrary n-qubit quantum state to within
a given precision ϵ? Improving prior work of Low, Kliuchnikov and Schaeffer, we show that the
optimal asymptotic scaling is Θ(sqrt{2^n log(1/ε)} + log(1/ε)) if we allow an unlimited number of ancilla qubits. We also show that this is the optimal T-count for implementing an arbitrary
diagonal n-qubit unitary to within error ϵ. We describe an application to batched synthesis of
single-qubit unitaries: we can approximate a tensor product of m = O(log log(1/ϵ)) arbitrary
single-qubit unitaries to within error ϵ with the same asymptotic T-count as is required to
approximate just one single-qubit unitary.
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ALF: Advertiser Large Foundation Model for Multi-Modal Advertiser Understanding
Sunny Rajagopalan
Alireza Golestaneh
Shubhra Chandra
Min Zhou
Jonathan Vronsky
Songbai Yan
2026
Preview abstract
We present ALF (Advertiser Large Foundation model), a multi-modal transformer architecture for understanding advertiser behavior and intent across text, image, video and structured data modalities. Through contrastive learning and multi-task optimization, ALF creates unified advertiser representations that capture both content and behavioral patterns. Our model achieves state-of-the-art performance on critical tasks including fraud detection, policy violation identification, and advertiser similarity matching. In production deployment, ALF reduces false positives by 90\% while maintaining 99.8\% precision on abuse detection tasks. The architecture's effectiveness stems from its novel combination of multi-modal transformations, intersample attention mechanism, spectrally normalized projections, and calibrated probabilistic outputs.
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ToolGrad: Efficient Tool-use Dataset Generation with Textual "Gradients"
Kohei Uehara
Haoyu Zhang
Jingtao Zhou
Lin Gu
Zheng Xu
Tatsuya Harada
ACL 2026 (2026)
Preview abstract
Prior work synthesizes tool-use LLM datasets by first generating a user query, followed by complex tool-use annotations like depth-first search (DFS). This leads to inevitable annotation failures and low efficiency in data generation. We introduce ToolGrad, an agentic framework that inverts this paradigm. ToolGrad first constructs valid tool-use chains through an iterative process guided by textual "gradients", and then synthesizes corresponding user queries. This "answer-first" approach led to ToolGrad-500, a dataset generated with more complex tool use, lower cost, and almost 100% pass rate. Experiments show that ToolGrad models outperform those trained on expensive baseline datasets and proprietary LLMs.
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Usability Hasn’t Peaked: Exploring How Expressive Design Overcomes the Usability Plateau
Alyssa Sheehan
Bianca Gallardo
Ying Wang
Proceedings of the 2026 CHI Conference on Human Factors in Computing Systems (CHI ’26), April 13–17, 2026, Barcelona, Spain (2026)
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Critics have argued that mobile usability has largely been optimized, and that only incremental gains are possible. We set out to explore if the newest generation of design systems, which promote greater flexibility and a return to design basics, could produce substantially more usable designs while maintaining or increasing aesthetic judgments. Through a study with 48 diverse participants completing tasks in 10 different applications, we found that in designs created following Material 3 Expressive guidelines, users fixated on the correct screen element for a task 33% faster, completed tasks 20% faster, and rated experiences more positively compared to versions designed using the previous Material design system. These improvements in performance and aesthetic ratings challenge the premise of a usability plateau and show that mobile usability has not peaked. We illustrate specific opportunities to make mobile experiences more usable by returning to design fundamentals while highlighting risks of added flexibility.
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PURPOSE: To introduce Cardio Load (CL), a metric quantifying cardiovascular work from all activities across the day, and to investigate its distribution by age, gender, and workout profiles. CL adapts the Training Impulse (TRIMP) model by leveraging continuous heart rate and movement data from wearables, enabling minute-level intensity estimation. We also discuss the derivation of weekly target loads, intended to guide fitness maintenance.
METHODS: A retrospective analysis was conducted on 31.2 million hours of wrist-worn wearable data collected over a six-week period. The dataset comprised a 40,000-subject subset (37.9% female) of consenting Google Pixel Watch® users in the United States, aged 18 to 80 years (18-39: 41.8%, 40-59: 43.5%, 60+: 14.6%). Measured data included minute-interval heart rate averages, resting and maximum heart rates, minute-interval averaged accelerometer log energy, and manually-logged or auto-detected activity types. Cardio Load scores and target loads were calculated daily for each subject and compared across age and gender. We also compared the proportions of CL gained during workouts and incidental daily activities for these groups.
RESULTS: Overall, the study population's mean ± SD weekly CL scores were 221 ± 156 (female) and 259 ± 169 (male). Median weekly Cardio Load (CL) values exhibited consistency for individuals between 30 and 75 years of age. When analyzed in five-year age groups, the coefficient of variation (CV%) of median weekly CL values within this age range was less than 4.5%, with younger and older subjects demonstrating higher and lower median CL, respectively. The median proportion of CL accumulated during structured workouts versus incidental daily activity was 41.0% (female) and 49.0% (male) for all subjects, though this varied considerably with average weekly workout duration. CV% of weekly target load and daily target load over 6 weeks was 23.6% and 35.2% respectively.
CONCLUSION: Cardio Load provides a continuous quantification of activity load from wearables, acknowledging both structured workouts and everydayincidental activity. CL is equitably rewarded for age ranges spanning 30-75 years. Weekly target loads were found to have little measurement variability and be more consistent and, consequently, more practical for planning training and physical activity than daily targets.
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Bi-level Hierarchical Neural Contextual Bandits for Online Recommendation
Yunzhe Qi
Yikun Ban
Allan Stewart
Chuanwei Ruan
Jiachuan He
Shishir Kumar Prasad
Haixun Wang
Jingrui He
Transactions on Machine Learning Research (2026)
Preview abstract
Contextual bandit algorithms aim to identify the optimal choice among a set of candidate arms, based on their contextual information. Among others, the neural contextual bandit algorithms have demonstrated generally superior performance compared to traditional linear and kernel-based methods. Nevertheless, neural methods are not inherently suitable to handle a large number of candidate arms due to their high computational cost when performing neural exploration.
Motivated by the widespread availability of arm category information (e.g., movie genres, retailer types), we formulate contextual bandits into a bi-level recommendation problem based on the accessible arm category information, and propose a novel neural bandit framework, named H2N-Bandit, which utilizes a bi-level hierarchical neural structure to mitigate the substantial computational cost found in conventional neural bandit methods.
To demonstrate its effectiveness, we provide the regret bound for H2N-Bandit under the over-parameterized neural bandit settings. Furthermore, to illustrate its efficiency, we conduct extensive experiments on multiple real-world public data sets with various specifications, showing that H2N-Bandit can significantly reduce the computational cost over existing non-linear methods while achieving better or comparable performances against state-of-the-art baselines.
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