Google Research

Annalisa Pawlosky


Annalisa Pawlosky is the founder and principal investigator for the Google Accelerated Science biochemistry and molecular biology laboratory, a unique laboratory specifically designed for building custom assays that integrate with mathematical models, including machine learning, to accelerate new findings in the biological sciences. Annalisa conducted her postdoctoral work under Jan Liphardt and Michael Clarke as a Stanford Molecular Imaging Scholar postdoctoral fellow, and focused on discovering the mechanism behind the role of Usp16 in stem cell senescence. For this work, she built dimerization dependent protein sensors (ddFPs) between Usp16 and histone H2A for single molecule live cell imaging assays with TIRF. Annalisa received her PhD from MIT in the Harvard-MIT Division of Health Sciences and Technology program under the supervision of Alexander van Oudenaarden with her thesis titled Single molecule techniques to probe decision-making processes in developmental biology. She initiated mammalian work in the van Oudenaarden laboratory, and focused on studying patterning in mammalian organs during embryonic development. In particular, she studied and modeled Notch pathway regulated mechanisms behind cellular patterning for mammalian auditory outer hair cells with single molecule RNA FISH (smFISH).

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