Annalisa Pawlosky
Annalisa Pawlosky is the founder and principal investigator for the Google Accelerated Science biochemistry and molecular biology laboratory, a unique laboratory specifically designed for building custom assays that integrate with mathematical models, including machine learning, to accelerate new findings in the biological sciences. Annalisa conducted her postdoctoral work under Jan Liphardt and Michael Clarke as a Stanford Molecular Imaging Scholar postdoctoral fellow, and focused on discovering the mechanism behind the role of Usp16 in stem cell senescence. For this work, she built dimerization dependent protein sensors (ddFPs) between Usp16 and histone H2A for single molecule live cell imaging assays with TIRF. Annalisa received her PhD from MIT in the Harvard-MIT Division of Health Sciences and Technology program under the supervision of Alexander van Oudenaarden with her thesis titled Single molecule techniques to probe decision-making processes in developmental biology. She initiated mammalian work in the van Oudenaarden laboratory, and focused on studying patterning in mammalian organs during embryonic development. In particular, she studied and modeled Notch pathway regulated mechanisms behind cellular patterning for mammalian auditory outer hair cells with single molecule RNA FISH (smFISH).
Research Areas
Authored Publications
Sort By
Google
ProtSeq: towards high-throughput, single-molecule protein sequencing via amino acid conversion into DNA barcodes
Jessica Hong
Michael Connor Gibbons
Ali Bashir
Diana Wu
Shirley Shao
Zachary Cutts
Mariya Chavarha
Ye Chen
Lauren Schiff
Mikelle Foster
Victoria Church
Llyke Ching
Sara Ahadi
Anna Hieu-Thao Le
Alexander Tran
Michelle Therese Dimon
Phillip Jess
iScience, 25 (2022), pp. 32
Machine learning guided aptamer discovery
Ali Bashir
Geoff Davis
Michelle Therese Dimon
Qin Yang
Scott Ferguson
Zan Armstrong
Nature Communications (2021)
