Artificial intelligence for Gleason grading of prostate biopsies -- current status and next steps
Abstract
Gleason grading of prostate biopsies is critical to the clinical management of men with prostate cancer. However, the challenge with high inter-pathologist variability leads to risks for under- and overtreatment. Artificial intelligence (AI) systems have shown promise to assist pathologists in performing Gleason grading, which could help address this problem. In this mini-review, we highlight studies reporting on the development of AI systems for Gleason grading and discuss remaining steps needed for widespread clinical implementation, as well as ongoing and future developments.