Google uses continuous streams of data from industry partners to deliver accurate results for various products to end users. Unexpected drops in incoming traffic can be an indication of an underlying issue and may be an early warning that remedial action may be necessary. Detecting such drops is non-trivial because streams are variable and noisy, with roughly regular spikes (in many different shapes) in traffic rate. We investigated the question of whether or not we can predict anomalies in these data streams. Our goal is to utilize Machine Learning and statistical approaches to classify anomalous drops in periodic, but noisy, traffic patterns. Since we do not have a large body of labeled examples to directly apply supervised learning for anomaly classification, we approached the problem in two parts. First we used TensorFlow to train our various models including DNNs, RNNs, and LSTMs to perform regression and predict the expected value in the time series. Second we created anomaly detection rules that compared the actual values to predicted values. Since the problem requires finding sustained anomalies, rather than just short delays or momentary inactivity in the data, our two detection methods focused on continuous sections of activity rather than individual data points. We tried multiple combinations of our models and rules and found that using the intersection of our two anomaly detection methods proved to be an effective method of detecting anomalies on almost all of our models. In the process we also found that not all data fell within our experimental assumptions, as one data stream had no periodicity, and therefore no time based model could predict it.