Computer dialogue systems are designed with the intention of supporting meaningful interactions with humans. Common modes of communication include speech, text, and physical gestures. In this work we explore a communication paradigm in which the input and output channels consist of music. Specifically, we examine the musical interaction scenario of call and response. We present a system that utilizes a deep autoencoder to learn semantic embeddings of musical input. The system learns to transform these embeddings in a manner such that reconstructing from these transformation vectors produces appropriate musical responses. In order to generate a response the system employs a combination of generation and unit selection. Selection is based on a nearest neighbor search within the embedding space and for real-time applica- tion the search space is pruned using vector quantization. The live demo consists of a person playing a midi keyboard and the computer generating a response that is played through a loudspeaker.